Hypertrophic cardiomyopathy, apical variant (Yamaguchi's Syndrome)

Hypertrophic cardiomyopathy, apical variant (Yamaguchi's Syndrome). The ECG demonstrates marked left ventricular hypertrophy (LVH) with deep T wave inversions in the precordial and limb leads. Yamaguchi's cardiomyopathy is characterized by isolated apical hypertrophy. The surface ECG shows LVH and T wave inversions predominantly in V3-V5 but often present in other leads. Apical hypertrophic cardiomyopathy as well as more common forms of hypertrophic cardiomyopathy are important causes of pseudo-infarct patterns. The initial report of Yamaguchi's syndrome can be found in Am J Cardiol 44:401,1979.