Cardiology Network Team's Page

Context The role of diet composition in response to overeating and energy dissipation in humans is unclear.

Objective To evaluate the effects of overconsumption of low, normal, and high protein diets on weight gain, energy expenditure, and body composition.

Design, Setting, and Participants A single-blind, randomized controlled trial of 25 US healthy, weight-stable male and female volunteers, aged 18…

The investigation in the Dutch scientific misconduct case has now spread to the Leiden University Medical Center, according to media reports in the Netherlands. The case first came to public attention last month when the Erasmus Medical Center in Rotterdam fired  prominent cardiovascular researcher Don Poldermans. (…

Lipitor (atorvastatin) was the top-selling prescription medication in the United States in 2010, earning its manufacturer, Pfizer, more than $7 billion in total revenue. The overall market for prescription lipid-lowering drugs continues to grow; this drug class had greater prescription volume than any other class in 2010, with statins dominating the market.1…

Background

Two treatments for smoking cessation—varenicline and bupropion—carry Boxed Warnings from the U.S. Food and Drug Administration (FDA) about suicidal/self-injurious behavior and depression. However, some epidemiological studies report an increased risk in smoking or smoking cessation independent of treatment, and differences between drugs are unknown.

Methodology

From the FDA's Adverse Event Reporting System (AERS) database from 1998 through September 2010…